10 Best Stain Removal Sprays for Killer Stains

Looking for the best stain removal sprays? This guide offers the top 10 choices to help you conquer even the toughest stains and keep your clothes looking their best!

Tired of stubborn stains on your clothes? Finding the perfect stain remover can be a real challenge. But don’t worry, I’m here to help you find the best ones!

I’ve gathered information from many different sources. This guide will help you choose the right stain remover. You’ll soon have fresh, clean clothes again.

List of Top 10 Stain Removal Sprays

Image Title Best For Price
Shout Active Enzyme Laundry Stain Remover Spray, Triple-Acting Formula Clings, Penetrates, and Lifts 100+ Types of Everyday Stains - Prewash Spray 22oz Shout Active Enzyme Laundry Stain Remover Spray, Triple-Acting Formula Clings, Penetrates, and Lifts 100+ Types of Everyday Stains – Prewash Spray 22oz

Shout Active Enzyme Laundry Stain Remover Spray is perfect for busy families and anyone who deals with messy kids, pets, or everyday spills that leave tough stains on clothes. It works fast and easy, so you can keep your laundry spotless without extra stress.

Miss Mouth's Messy Eater Stain Treater Spray - 4oz Stain Remover - Newborn & Baby Essentials - No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric Miss Mouth’s Messy Eater Stain Treater Spray – 4oz Stain Remover – Newborn & Baby Essentials – No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

This stain remover spray is perfect for parents with newborn babies and toddlers who need a quick fix for messy food and drink spills. It’s also great for anyone with upholstery or clothes facing grease, coffee, or blood stains.

OxiClean Max Force Laundry Stain Remover Spray, Newborn & Baby Essentials, Stain Treater, 12 fl oz, 3-Pack OxiClean Max Force Laundry Stain Remover Spray, Newborn & Baby Essentials, Stain Treater, 12 fl oz, 3-Pack

This easy-to-use spray is perfect for busy parents with newborns and babies who need to tackle stubborn stains on clothes quickly. It’s also great for families dealing with kids’ messy adventures from food, paint, or play.

Shout Active Enzyme Laundry Stain Remover Spray for Clothes, Triple-Acting Formula Clings, Penetrates, and Lifts Tough & Everyday Stains - Prewash Refill 60oz (1.7L) Shout Active Enzyme Laundry Stain Remover Spray for Clothes, Triple-Acting Formula Clings, Penetrates, and Lifts Tough & Everyday Stains – Prewash Refill 60oz (1.7L)

Tired of stubborn stains ruining your favorite clothes? This powerful stain remover is perfect for busy people who want clean clothes without the hassle. It’s quick, easy, and works on all sorts of stains!

Shout Advanced Laundry Stain Remover Gel for Clothes Laundry, Breaks down stubborn, dried-in, and tough stains - 22oz Spray Shout Advanced Laundry Stain Remover Gel for Clothes Laundry, Breaks down stubborn, dried-in, and tough stains – 22oz Spray

This Shout Advanced Laundry Stain Remover is perfect for everyone. It is made for people who want to remove tough stains easily.

Miss Mouth's Messy Eater Stain Treater Spray - 4oz 2 Pack Stain Remover - Newborn & Baby Essentials - No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric Miss Mouth’s Messy Eater Stain Treater Spray – 4oz 2 Pack Stain Remover – Newborn & Baby Essentials – No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

This product is perfect for everyone! It’s great for babies, toddlers, and even adults. It helps clean up messy stains quickly and easily.

Spray N'Wash Pre-treat Laundry Stain Remover Bottles, Clear, 1.37 Pound (Pack of 6), 132 Fl Oz Spray N’Wash Pre-treat Laundry Stain Remover Bottles, Clear, 1.37 Pound (Pack of 6), 132 Fl Oz

Spray N’Wash is perfect for busy parents tackling tough stains from kids’ adventures or messy meals. It’s also ideal for anyone who wants an easy spray to keep clothes looking great without stress.

Grandma's Secret Spot Remover Laundry Spray - Chlorine, Bleach and Toxin-Free for Clothes - Fabric Stain Remover Removes Oil, Paint, Blood and Pet Stains - 16 oz & 2 oz Combo, DuoPack Grandma’s Secret Spot Remover Laundry Spray – Chlorine, Bleach and Toxin-Free for Clothes – Fabric Stain Remover Removes Oil, Paint, Blood and Pet Stains – 16 oz & 2 oz Combo, DuoPack

Grandma’s Secret Spot Remover is perfect for parents who need a gentle way to clean baby stains from diaper leaks or messy foods. It also works great for pet owners dealing with tough pet stains or anyone facing oil, blood, or grass spots on clothes without fearing fabric damage.

Zout Laundry Stain Remover Spray, Triple Enzyme Formula Removes the Toughest Stains, Made in the USA, 22 Ounce Bottles, 2-Pack Zout Laundry Stain Remover Spray, Triple Enzyme Formula Removes the Toughest Stains, Made in the USA, 22 Ounce Bottles, 2-Pack

This Zout Laundry Stain Remover Spray is perfect for everyone. It is for anyone who wants to remove tough stains easily.

Stardrops - The Pink Stuff - The Miracle Laundry Oxi Stain Remover Spray 500ml Stardrops – The Pink Stuff – The Miracle Laundry Oxi Stain Remover Spray 500ml

This product is perfect for busy parents who deal with greasy kid messes and stubborn stains on clothes every day. It’s also great for anyone who wants an easy way to keep fabrics looking fresh without extra effort.

Detailed Reviews

Our expert picks for the best stain removal sprays come from deep reviews of top products like Shout, OxiClean, and Zout. These sprays quickly lift tough stains off clothes and fabrics, saving time and effort. Trust our guide to find the right one for everyday messes. Discover how these easy-to-use options keep your laundry fresh and clean.

1. Shout Active Enzyme Laundry Stain Remover Spray, Triple-Acting Formula Clings, Penetrates, and Lifts 100+ Types of Everyday Stains – Prewash Spray 22oz

Shout Active Enzyme Laundry Stain Remover Spray, Triple-Acting Formula Clings, Penetrates, and Lifts 100+ Types of Everyday Stains - Prewash Spray 22oz

Tired of stubborn stains ruining your favorite clothes? Shout Active Enzyme Laundry Stain Remover is here to help. This powerful spray makes stain removal simple and fuss-free. Get ready to say goodbye to blemishes and hello to fresh, clean fabrics!

It clings, penetrates, and lifts stains with ease. The triple-acting formula works on 100+ types of everyday stains.

Use on whites and colors for amazing results. It’s quick, easy to use, and works even a week later.

Pros Cons
  • Erases 100+ stains fast and easy!
  • Clings deep to penetrate and lift dirt.
  • Works on all fabrics and wash types.
  • Spray now, wash later up to a week!
  • Made from 25% recycled plastic for eco-friendly use.
  • May not remove all stains.
  • Requires pre-treatment before washing.
  • Bottle is not fully recycled.

Perfect For:

Shout Active Enzyme Laundry Stain Remover Spray is perfect for busy families and anyone who deals with messy kids, pets, or everyday spills that leave tough stains on clothes. It works fast and easy, so you can keep your laundry spotless without extra stress.

Ready to Purchase?

2. Miss Mouth’s Messy Eater Stain Treater Spray – 4oz Stain Remover – Newborn & Baby Essentials – No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

Miss Mouth's Messy Eater Stain Treater Spray - 4oz Stain Remover - Newborn & Baby Essentials - No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

Toss stubborn stains out the door with Miss Mouth’s Messy Eater stain spray. This 4oz bottle blasts away food, grease, and coffee from laundry, underwear, and fabrics. Wave goodbye to dry cleaning hassles.

Feel safe knowing it’s EPA Safer Choice certified for top health standards. It wipes out tough baby messes like fruit juice, formula, and blood from kids’ clothes.

Keep it simple: Ditch excess gunk first. Spray on and rub lightly, then wash as usual. Repeat if needed for spotless results.

Pros Cons
  • Fast stain removal for clothes, carpets, and more!
  • Safe for family; EPA Safer Choice certified.
  • Magic on fresh and set-in stains!
  • Easy to use: Just spray, rub, and wash!
  • May not work on all stain types.
  • Repeat applications might be needed.
  • Effectiveness can depend on stain age.

Perfect For:

This stain remover spray is perfect for parents with newborn babies and toddlers who need a quick fix for messy food and drink spills. It’s also great for anyone with upholstery or clothes facing grease, coffee, or blood stains.

Ready to Purchase?

3. OxiClean Max Force Laundry Stain Remover Spray, Newborn & Baby Essentials, Stain Treater, 12 fl oz, 3-Pack

OxiClean Max Force Laundry Stain Remover Spray, Newborn & Baby Essentials, Stain Treater, 12 fl oz, 3-Pack

OxiClean Max Force is a top stain remover spray. It comes in a 12 fl oz, 3-pack for easy use on clothes.

This spray fights tough stains like grease, mud, and baby food. It works on all washable fabrics, even baby items. Just spray, wait, and wash for clean results.

Pros Cons
  • Erases tough stains like grease and blood easily
  • Spray now, wash later up to seven days ahead
  • Safe for baby clothes and all fabric types
  • Gentle on colors without bleach or dyes
  • Powerful yet easy to use on any machine wash
  • Wait up to 7 days before washing clothes
  • May not fully remove very tough stains
  • Only for fabrics that machine wash

Perfect For:

This easy-to-use spray is perfect for busy parents with newborns and babies who need to tackle stubborn stains on clothes quickly. It’s also great for families dealing with kids’ messy adventures from food, paint, or play.

Ready to Purchase?

4. Shout Active Enzyme Laundry Stain Remover Spray for Clothes, Triple-Acting Formula Clings, Penetrates, and Lifts Tough & Everyday Stains – Prewash Refill 60oz (1.7L)

Shout Active Enzyme Laundry Stain Remover Spray for Clothes, Triple-Acting Formula Clings, Penetrates, and Lifts Tough & Everyday Stains - Prewash Refill 60oz (1.7L)

Say goodbye to stubborn stains with Shout Active Enzyme Stain Remover! This powerful spray tackles a wide variety of stains. It’s the perfect solution for your laundry needs.

This triple-acting formula clings, penetrates, and lifts. It’s safe for all machine-washable fabrics.

Get the 60oz refill bottle today. It’s easy to use: just spray, rub, and wash. Your clothes will look fresh and clean!

Pros Cons
  • Powerful 60oz refill tackles many tough stains fast.
  • Triple-action formula clings, penetrates, and lifts stains.
  • Works on whites and colors in any water temperature.
  • Concentrated spray beats in-wash stain removers.
  • Spray, rub, and wash—simple and long-lasting stain care.
  • Messy spray could spill or stain hands.
  • Strong smell from formula might linger.
  • Might not remove aged or set-in stains fully.

Perfect For:

Tired of stubborn stains ruining your favorite clothes? This powerful stain remover is perfect for busy people who want clean clothes without the hassle. It’s quick, easy, and works on all sorts of stains!

Ready to Purchase?

5. Shout Advanced Laundry Stain Remover Gel for Clothes Laundry, Breaks down stubborn, dried-in, and tough stains – 22oz Spray

Shout Advanced Laundry Stain Remover Gel for Clothes Laundry, Breaks down stubborn, dried-in, and tough stains - 22oz Spray

Shout Advanced is a strong stain remover gel. It breaks down tough stains from food and drinks.

This thick gel works on heavy duty messes. You can wash your clothes later, even a week after.

Spray the stain. Rub it gently. Remove stubborn spots fast.

Pros Cons
  • Tackles tough stains from food and drinks with ease.
  • Powerful gel removes dried-in dirt quickly.
  • Spray, rub, wash – now or up to a week later.
  • Works great on all clothes, whites and colors.
  • 70% stronger than regular Shout for better results.
  • May not remove every stain completely.
  • Spray application can be messy.
  • Scent may be too strong for some.

Perfect For:

This Shout Advanced Laundry Stain Remover is perfect for everyone. It is made for people who want to remove tough stains easily.

Ready to Purchase?

6. Miss Mouth’s Messy Eater Stain Treater Spray – 4oz 2 Pack Stain Remover – Newborn & Baby Essentials – No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

Miss Mouth's Messy Eater Stain Treater Spray - 4oz 2 Pack Stain Remover - Newborn & Baby Essentials - No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

Miss Mouth’s Messy Eater Spray fights stains fast. It works on clothes, carpets, and couches. It is safe for babies and families.

This spray removes juice, baby food, formula, grease, and blood. It works on new and old stains. It is EPA Safer Choice certified.

Use on dry or damp stains. Spray, rub, and wash.

Pros Cons
  • Powerful and fast stain remover works in a flash.
  • Safer Choice certified for family-friendly safety.
  • Tackles tough stains like juice, food, and blood.
  • Easy to use on clothes, carpets, and fabrics.
  • Removes both fresh and old messes effectively.
  • May not remove all tough stains.
  • Requires a second application sometimes.
  • Can be pricy compared to other stain removers.

Perfect For:

This product is perfect for everyone! It’s great for babies, toddlers, and even adults. It helps clean up messy stains quickly and easily.

Ready to Purchase?

7. Spray N’Wash Pre-treat Laundry Stain Remover Bottles, Clear, 1.37 Pound (Pack of 6), 132 Fl Oz

Spray N'Wash Pre-treat Laundry Stain Remover Bottles, Clear, 1.37 Pound (Pack of 6), 132 Fl Oz

Spray N’Wash is a powerful stain remover that tackles the toughest stains on your clothes. It penetrates deep and eliminates messes to keep your washables looking fresh.

This pack includes six convenient 22 oz trigger spray bottles for easy use. It is safe for colorfast washables and works in all temperatures.

Pros Cons
  • Eliminates tough stains quickly with powerful formula.
  • Safe for all colorfast fabrics.
  • Convenient spray bottle for easy use.
  • Works in any water temperature.
  • Bulk pack gives you plenty to last.
  • May not work on all types of stains.
  • Trigger spray may leak or clog over time.
  • Large pack may be too much for small loads.

Perfect For:

Spray N’Wash is perfect for busy parents tackling tough stains from kids’ adventures or messy meals. It’s also ideal for anyone who wants an easy spray to keep clothes looking great without stress.

Ready to Purchase?

8. Grandma’s Secret Spot Remover Laundry Spray – Chlorine, Bleach and Toxin-Free for Clothes – Fabric Stain Remover Removes Oil, Paint, Blood and Pet Stains – 16 oz & 2 oz Combo, DuoPack

Grandma's Secret Spot Remover Laundry Spray - Chlorine, Bleach and Toxin-Free for Clothes - Fabric Stain Remover Removes Oil, Paint, Blood and Pet Stains - 16 oz & 2 oz Combo, DuoPack

Tired of tough stains ruining your clothes? Grandma’s Secret Spot Remover is here! It easily removes stains without harming your fabrics. Get ready for stain-free clothes!

This powerful formula tackles oil, paint, blood, and pet stains. It even works on old, set-in stains.

Plus, it’s safe for baby clothes! The pleasant citrus fragrance is an added bonus.

Pros Cons
  • Tough on stains, gentle on clothes.
  • Removes even old, set-in stains.
  • Works on many types of stains.
  • Safe for baby clothes.
  • Easy to use, stains vanish fast.
  • May not work on every single stain type.
  • Citrus scent might not appeal to everyone.

Perfect For:

Grandma’s Secret Spot Remover is perfect for parents who need a gentle way to clean baby stains from diaper leaks or messy foods. It also works great for pet owners dealing with tough pet stains or anyone facing oil, blood, or grass spots on clothes without fearing fabric damage.

Ready to Purchase?

9. Zout Laundry Stain Remover Spray, Triple Enzyme Formula Removes the Toughest Stains, Made in the USA, 22 Ounce Bottles, 2-Pack

Zout Laundry Stain Remover Spray, Triple Enzyme Formula Removes the Toughest Stains, Made in the USA, 22 Ounce Bottles, 2-Pack

Zout Laundry Stain Remover Spray fights the toughest stains on clothes. It works fast with a triple enzyme formula to clean grass, dirt, blood, and food messes.
It uses one enzyme for protein stains such as blood and grass. A second enzyme handles stains like tomato and BBQ sauce. The third tackles fat stains from salad dressing and butter.
This spray is safe for most colorfast fabrics and made in the USA. Just spray the stain fully and rub it in. Wait 5 minutes, then wash like normal.
Zout clears set-in stains in one try. No need for extra treatments or washes. It saves you time and keeps clothes fresh.

Pros Cons
  • Zout removes even the toughest stains easily!
  • Triple enzyme power attacks all kinds of stains.
  • Safe for most colorfast washable fabrics.
  • Just one application washes stains away fast!
  • Strong odor lingers on clothes.
  • Needs 5 minutes to work, slowing chores.
  • May fade colors on fragile fabrics.

Perfect For:

This Zout Laundry Stain Remover Spray is perfect for everyone. It is for anyone who wants to remove tough stains easily.

Ready to Purchase?

10. Stardrops – The Pink Stuff – The Miracle Laundry Oxi Stain Remover Spray 500ml

Stardrops - The Pink Stuff - The Miracle Laundry Oxi Stain Remover Spray 500ml

Tired of stubborn stains ruining your clothes? The Pink Stuff Miracle Laundry Oxi Stain Remover Spray is here to help! It’s designed to lift away even the toughest marks.

This powerful spray uses Oxi Action technology. It’s safe for a wide range of fabrics, including whites and colors.

It’s easy to use. Just spray and wash. Your clothes will look fresh and clean.

Pros Cons
  • Eliminates tough stains like grease and oil.
  • Deep-cleans fabrics with Oxi Action power.
  • Safe on all types of whites and colors.
  • Easy spray for quick stain pre-treatment.
  • From a trusted brand you can rely on.
  • May not remove very tough stains.
  • Strong smell could bother some users.
  • Might need multiple sprays for success.

Perfect For:

This product is perfect for busy parents who deal with greasy kid messes and stubborn stains on clothes every day. It’s also great for anyone who wants an easy way to keep fabrics looking fresh without extra effort.

Ready to Purchase?

Buying Guide

Stain removers make cleaning clothes simple. They tackle tough spots on fabrics. Pick one that fits your needs.

Users love how Shout clings and lifts stains from daily messes, leaving clothes fresh after a easy spray and wash. A mom shared that Miss Mouth’s spray safely wiped blood and formula from baby clothes without dry cleaning. OxiClean users say it blasts grease off in one go, perfect for families.

  • Stain Types: Check what stains the remover handles. Look for ones that fight food, grease, or blood. This ensures it works for your common messes.
  • Safety for Fabrics: Choose options safe on whites and colors. Some are great for baby items or sensitive skin. Avoid ones that might fade prints.
  • Product Size: Pick sizes that last for your laundry load. Larger bottles offer value for big families. Small sprays are handy for on-the-go fixes.
  • Ease of Use: Select sprays that apply quickly with a trigger. Rub and wash methods save time. No soaking needed means fast cleaning.
  • Certifications and Ingredients: Go for EPA safe choices if health matters. Enzyme formulas break down stains naturally. Check for pleasant smells without harsh chemicals.
  • Value for Money: Compare packs for savings. Refills cost less over time. Effective removers reduce wasted washes.