Looking for the best high-efficiency compatible laundry detergents? Discover top-rated HE detergents that tackle tough stains, leave clothes fresh, and keep your machine running smoothly—all while saving time, money, and protecting sensitive skin.
High-efficiency (HE) washing machines need the right detergent to work best. Using the wrong one can cause problems like too many suds or not enough cleaning. We’ve found the top HE-compatible detergents to make your laundry easy and effective.
These detergents are powerful yet gentle on clothes. They remove tough stains and odors without harming your machine. Plus, they come in fresh scents and concentrated formulas to save you time and money.
Whether you prefer long-lasting freshness or sensitive skin-friendly options, we’ve got you covered. Read on to find the perfect HE detergent for your laundry needs.
List of Top 10 High-Efficiency Compatible Laundry Detergents
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ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst, 128 Loads Liquid Laundry Detergent, 166.5 Fl oz |
Busy families, active individuals, or anyone tackling tough odors and stubborn stains will love this detergent. It delivers deep cleaning, lasting freshness, and cost-effective value with trusted baking soda power. |
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Clorox Fraganzia Liquid Laundry Detergent in Lavendar Scent – HE Compatible for All Front and Top Load Washing Machines, High Efficiency Laundry Detergent Compatible, 100 Fl Oz |
Clorox Fraganzia Lavendar Detergent is perfect for anyone who loves a soothing lavender scent and crisp eucalyptus aroma in their laundry. It works in all HE washing machines, handles 65 loads, and leaves clothes smelling fresh. |
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Tide Plus Boost of Ultra Downy Liquid Laundry Detergent, April Fresh Scent, 132 fl oz, 94 Loads, Laundry Detergent Liquid with Long-Lasting Freshness |
This product is perfect for busy households wanting powerful cleaning and long-lasting freshness. It works in all washing machines, uses a concentrated formula, and fights stains even in cold water. |
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Tide Liquid Laundry Detergent, Original Scent, 125 fl oz, 100 Loads, Boosted Clean Even in Cold Water with Concentrated Washing Soap |
This Tide Liquid Laundry Detergent is perfect for busy households needing tough stain removal and cold water efficiency. Its 6X Boosted Clean formula fights grease and stains with 10X power, while the concentrated design cuts waste and lasts 100 loads. |
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Gain Odor Defense Liquid Laundry Detergent, Super Fresh Blast Scent, 194 fl oz, 134 loads, 2 in 1, Laundry Detergent Liquid Soap, HE compatible |
This detergent is perfect for those who want long-lasting freshness and tough odor removal. Lasts up to 6 weeks, fights odors, works in cold water, and is HE compatible for 134 loads. |
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ARM & HAMMER Liquid Laundry Detergent, Clean Burst Fresh, 170 fl oz, 170 Loads, HE Laundry Detergent Liquid |
Busy families and HE washer users love this detergent for powerful stain removal and a fresh, clean scent. Its concentrated formula handles tough dirt and odors while being gentle on machines and clothes. |
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Persil Original Everyday Clean, Liquid Laundry Detergent, High Efficiency (HE), Deep Stain Removal, Ultra Concentrated, 82.5 fl oz, 110 Loads |
Busy parents and working professionals love Persil Original. It deep cleans tough stains fast, keeps colors bright and whites dazzling, and works brilliantly in high-efficiency machines. With ultra-concentrated power, you use less and get premium results every single load. |
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Tide Ultra Oxi Boost Liquid Laundry Detergent, 132 fl oz, 94 Loads, Advanced Stain Remover, Laundry Detergent Liquid with Extra Oxi Power |
This detergent is perfect for anyone with tough stains and lingering odors. Its built-in pre-treaters, Ultra OXI power, and concentrated formula deliver a deep clean while making each load last longer. |
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Clorox Fraganzia Liquid Laundry Detergent in Ocean Scent – HE Compatible for All Front and Top Load Washing Machines, High Efficiency Laundry Detergent Compatible, 40 Fl Oz |
Perfect for anyone who loves fresh, long-lasting scents in their laundry. Ideal for homes with HE washing machines needing a light, beachy aroma and up to 26 clean loads. |
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all free clear, Original, Liquid Laundry Detergent for Sensitive Skin, Unscented and Hypoallergenic, Concentrated, 82.5oz, 110 Loads |
Perfect for people with sensitive skin, this detergent is #1 recommended by dermatologists, allergists, and pediatricians. No perfumes, dyes, or harsh residues make it gentle yet effective for everyday cleaning. |
Detailed Reviews
Discover expert-tested, customer-approved HE-compatible laundry detergents that deliver powerful stain removal, long-lasting freshness, and gentle care for every load. These top picks tackle tough odors, work in all machines, and offer scent choices from crisp ocean to soothing lavender. Whether you need sensitive-skin formulas, eco-friendly options, or budget-friendly jugs, this guide ensures clean, fresh clothes with every wash. Trust our data-driven rankings to find your perfect match—no guesswork, just results.
1. ARM & HAMMER Plus OxiClean Odor Blasters Fresh Burst, 128 Loads Liquid Laundry Detergent, 166.5 Fl oz
ARM & HAMMER Plus OxiClean Odor Blasters is a powerful liquid laundry detergent. It comes in a 166.5 fl oz bottle and can clean up to 128 loads.
This detergent fights tough odors and removes stains effectively. It contains Baking Soda and OxiClean Stain Fighters for lasting freshness and cleanliness.
Enjoy clean clothes that smell great. This detergent is easy to use. It’s a trusted choice for families.
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Perfect For:
Busy families, active individuals, or anyone tackling tough odors and stubborn stains will love this detergent. It delivers deep cleaning, lasting freshness, and cost-effective value with trusted baking soda power.
Ready to Purchase?
2. Clorox Fraganzia Liquid Laundry Detergent in Lavendar Scent – HE Compatible for All Front and Top Load Washing Machines, High Efficiency Laundry Detergent Compatible, 100 Fl Oz
Clorox Fraganzia Liquid Laundry Detergent in Lavendar Scent makes laundry day enjoyable. It gives your clothes a fresh and lasting fragrance.
This detergent can wash about 65 loads. It is safe for all front and top load washers. Enjoy the soothing scent of lavender while cleaning your clothes.
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Clorox Fraganzia Lavendar Detergent is perfect for anyone who loves a soothing lavender scent and crisp eucalyptus aroma in their laundry. It works in all HE washing machines, handles 65 loads, and leaves clothes smelling fresh.
Ready to Purchase?
3. Tide Plus Boost of Ultra Downy Liquid Laundry Detergent, April Fresh Scent, 132 fl oz, 94 Loads, Laundry Detergent Liquid with Long-Lasting Freshness
Looking for a powerful and fresh laundry solution? Tide Plus Boost of Ultra Downy gives you both. It combines Tide’s cleaning strength with Downy’s iconic April Fresh scent. Your clothes stay clean and smell great.
This liquid detergent is concentrated, so a little goes a long way. It works in all machines, whether they are HE or non-HE. You’ll get 94 loads from this 132 fl oz bottle, making it a smart choice for busy households.
Trust the Tide Plus Collection for top-quality cleaning. As part of America’s #1 detergent brand, it tackles all common stains. It even works in cold water to keep your laundry looking its best.
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Perfect For:
This product is perfect for busy households wanting powerful cleaning and long-lasting freshness. It works in all washing machines, uses a concentrated formula, and fights stains even in cold water.
Ready to Purchase?
4. Tide Liquid Laundry Detergent, Original Scent, 125 fl oz, 100 Loads, Boosted Clean Even in Cold Water with Concentrated Washing Soap
Tide Liquid Laundry Detergent is designed to clean your clothes thoroughly. It has a fresh original scent that lasts. You can get up to 100 loads with one jug.
This formula is extra strong. It fights 100% of stains and grease. Tide works well in cold water and all machine cycles.
It’s easy to use. Just pour the right amount into your machine. Tide keeps your laundry fresh and clean all day long.
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Perfect For:
This Tide Liquid Laundry Detergent is perfect for busy households needing tough stain removal and cold water efficiency. Its 6X Boosted Clean formula fights grease and stains with 10X power, while the concentrated design cuts waste and lasts 100 loads.
Ready to Purchase?
5. Gain Odor Defense Liquid Laundry Detergent, Super Fresh Blast Scent, 194 fl oz, 134 loads, 2 in 1, Laundry Detergent Liquid Soap, HE compatible
Gain Odor Defense Liquid Laundry Detergent fights smells and leaves clothes fresh. Its Super Fresh Blast Scent lasts up to 6 weeks after washing. It removes tough odors, not just covers them.
This detergent works in cold water and suits all washers, including HE models. One 194 fl oz bottle handles 134 loads, and pairs with Gain Scent Booster or Softener for more freshness.
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Perfect For:
This detergent is perfect for those who want long-lasting freshness and tough odor removal. Lasts up to 6 weeks, fights odors, works in cold water, and is HE compatible for 134 loads.
Ready to Purchase?
6. ARM & HAMMER Liquid Laundry Detergent, Clean Burst Fresh, 170 fl oz, 170 Loads, HE Laundry Detergent Liquid
Get Tough Stains Out with ARM & HAMMER Liquid Laundry Detergent! This Clean Burst Fresh formula is designed to tackle dirt and odors, leaving clothes smelling fresh and feeling clean. One 170 fl oz bottle gives you 170 loads of laundry power.
This concentrated detergent is packed with 2X powerful stain fighters to get your clothes looking their best. It’s perfect for everything from everyday clothes to towels and sheets. Plus, it’s safe for both standard and HE washers.
Try ARM & HAMMER Liquid Laundry Detergent today and experience the fresh scent of clean! Get your clothes cleaner with the power of ARM & HAMMER Baking Soda.
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Perfect For:
Busy families and HE washer users love this detergent for powerful stain removal and a fresh, clean scent. Its concentrated formula handles tough dirt and odors while being gentle on machines and clothes.
Ready to Purchase?
7. Persil Original Everyday Clean, Liquid Laundry Detergent, High Efficiency (HE), Deep Stain Removal, Ultra Concentrated, 82.5 fl oz, 110 Loads
Get ready for Persil Original Everyday Clean! This liquid laundry detergent offers a premium deep clean. It’s perfect for all your washing needs.
Persil keeps your clothes looking great. It helps prevent color fading. Your clothes will look newer for longer.
This detergent is ultra-concentrated. You get more cleaning power with less.
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Perfect For:
Busy parents and working professionals love Persil Original. It deep cleans tough stains fast, keeps colors bright and whites dazzling, and works brilliantly in high-efficiency machines. With ultra-concentrated power, you use less and get premium results every single load.
Ready to Purchase?
8. Tide Ultra Oxi Boost Liquid Laundry Detergent, 132 fl oz, 94 Loads, Advanced Stain Remover, Laundry Detergent Liquid with Extra Oxi Power
Tide Ultra Oxi Boost is a powerful laundry detergent. It comes in a 132 fl oz bottle, enough for 94 loads.
It has built-in pre-treaters for tough stains. The concentrated formula works efficiently.
This detergent tackles odors and keeps clothes fresh. Trust America’s #1 detergent brand for clean results.
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Perfect For:
This detergent is perfect for anyone with tough stains and lingering odors. Its built-in pre-treaters, Ultra OXI power, and concentrated formula deliver a deep clean while making each load last longer.
Ready to Purchase?
9. Clorox Fraganzia Liquid Laundry Detergent in Ocean Scent – HE Compatible for All Front and Top Load Washing Machines, High Efficiency Laundry Detergent Compatible, 40 Fl Oz
Clorox Fraganzia gives your laundry a fresh, beachy scent. It’s perfect for a scent-sational wash every time.
This 40oz bottle cleans up to 26 loads. It works in all washing machines, front or top load.
The Ocean scent is light and crisp. It’s HE compatible and easy to use.
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Perfect For:
Perfect for anyone who loves fresh, long-lasting scents in their laundry. Ideal for homes with HE washing machines needing a light, beachy aroma and up to 26 clean loads.
Ready to Purchase?
10. all free clear, Original, Liquid Laundry Detergent for Sensitive Skin, Unscented and Hypoallergenic, Concentrated, 82.5oz, 110 Loads
Sensitive skin? Meet your new best friend.
all free clear is the #1 detergent recommended by dermatologists and allergists. No perfumes, no dyes—just a powerful, gentle clean you can trust.
Now more concentrated, so every drop pulls out more dirt, oil, and allergens. Your clothes come out truly clean, without harsh residues that can irritate skin.
Safe for your family and the planet, with EPA Safer Choice certification and biodegradable ingredients. Works great in cold water and all HE machines—plus, it’s septic-safe.
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Perfect For:
Perfect for people with sensitive skin, this detergent is #1 recommended by dermatologists, allergists, and pediatricians. No perfumes, dyes, or harsh residues make it gentle yet effective for everyday cleaning.
Ready to Purchase?
Buying Guide
Shopping for the best high-efficiency (HE) laundry detergents can be a game-changer for your laundry routine. The right detergent not only cleans effectively but also protects your machine.
Here are the key factors to consider when buying HE-compatible laundry detergents:
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Cleaning Power: Look for detergents that effectively remove tough stains and odors. A powerful formula ensures your clothes come out fresh and clean every time.
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Compatibility: Ensure the detergent is specifically labeled as HE-compatible. This guarantees it works well with your high-efficiency washing machine, preventing excess suds and ensuring optimal performance.
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Scent Options: Choose a detergent with a scent you love. Fresh scents can make laundry day more enjoyable, while unscented options are great for sensitive skin.
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Concentration: Concentrated formulas are more efficient, requiring less detergent per load. This not only saves you money but also reduces waste.
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Skin Sensitivity: If you or your family members have sensitive skin, opt for hypoallergenic detergents. These are free from harsh chemicals and fragrances, making them gentle on the skin.
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Eco-Friendliness: Consider detergents with biodegradable ingredients and eco-friendly packaging. This choice is better for the environment and can be safer for your family.
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Load Capacity: Check how many loads the detergent can handle. Larger bottles may offer better value for money, especially for busy households.
By keeping these factors in mind, you can find the perfect HE-compatible laundry detergent that meets your needs and enhances your laundry experience!