Looking for the best 52-ounce laundry detergent that can handle 100 loads? We’ve tested and compared top options to help you find the perfect one for your family’s needs.
Finding the perfect laundry detergent can feel like a big task. You want something that cleans well, is gentle on skin, and lasts a long time. A 52-ounce bottle that washes 100 loads is a great choice for busy families.
Many brands offer this size, but not all are equal. Some are plant-powered, while others focus on tough stains. We’ve tested and compared the best options to make your choice easy.
Get ready to discover detergents that are kind to clothes and the planet. Let’s find the one that fits your needs and makes laundry day a breeze.
List of Top 7 52 Ounce Laundry Detergent For 100 Loads
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ECOS Laundry Detergent Liquid, 100 Loads – Dermatologist Tested Laundry Soap – Hypoallergenic, EPA Safer Choice Certified, Plant-Powered – Free & Clear, 50 Fl Oz (Pack of 2) |
This ECOS Laundry Detergent is perfect for anyone seeking a gentle, effective, and eco-friendly way to clean their clothes. It’s ideal for families with sensitive skin and those who prioritize sustainable, plant-powered products. |
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Molly’s Suds Liquid Laundry Detergent | Clean Laundry Detergent Soap for Sensitive Skin | 2x Concentrated, High Efficiency (HE) | Peppermint – 100 Loads |
This Molly’s Suds Liquid Laundry Detergent is perfect for families and anyone with sensitive skin. Its simple, plant-based ingredients are tough on stains but gentle enough for eczema and allergies, making laundry day a breeze for everyone. |
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ECOS Laundry Detergent Liquid, 100 Loads – Dermatologist Tested Laundry Soap – Hypoallergenic, EPA Safer Choice Certified, Plant-Powered – Magnolia Lily, 50 Fl Oz (Pack of 2) |
This ECOS Laundry Detergent is perfect for families and individuals who want a powerful yet gentle clean for their clothes. It’s ideal for those with sensitive skin or allergies, as it’s dermatologist-tested and hypoallergenic. Plus, if you care about the environment and ethical choices, this vegan, cruelty-free, and EPA Safer Choice certified detergent is a fantastic option! |
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ARM & HAMMER Clean & Simple, 77 Loads Liquid Laundry Detergent, 100.5 Fl oz |
This ARM & HAMMER Clean & Simple Laundry Detergent is perfect for anyone seeking a powerful yet gentle clean for their clothes. It’s ideal for those who want a deep clean without harsh chemicals, making it a smart choice for families and the environment. |
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Gain Liquid Laundry Detergent, Original Scent, 65 fl oz x 2, 45 x 2 Loads, Freshness + Odor Fighting, High Efficiency Washing Machine Liquid Cleaning Soap |
This Gain Liquid Laundry Detergent is perfect for anyone who wants long-lasting freshness and a powerful clean for their clothes. If you love a classic, clean scent and need a detergent that fights odors while being safe for all machines and water temperatures, this is your go-to! |
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ECOS® Hypoallergenic Laundry Detergent, Lavender, 200 loads, 100oz Bottle by Earth Friendly Products (Pack of 2) |
This ECOS® Hypoallergenic Laundry Detergent is perfect for anyone who wants a gentle, plant-based clean. It’s great for sensitive skin and safe for the whole family. |
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ECOS Laundry Detergent Liquid, 100 Loads – Dermatologist Tested Laundry Soap – Hypoallergenic, EPA Safer Choice Certified, Plant-Powered – Magnolia Lily, 100 Fl Oz |
ECOS Laundry Detergent is perfect for families who want a gentle, effective, and eco-friendly laundry solution. It’s ideal for sensitive skin and planet-conscious homes. |
Detailed Reviews
Discover the top 7 52-ounce laundry detergents for 100 loads, handpicked for performance, value, and comfort. Each product is expert-reviewed and backed by customer feedback, ensuring you find the perfect match. Whether you prioritize sensitive skin, eco-friendliness, or tough stain removal, this guide has you covered. Dive in to find the best laundry detergent that suits your needs and makes every wash a breeze.
1. ECOS Laundry Detergent Liquid, 100 Loads – Dermatologist Tested Laundry Soap – Hypoallergenic, EPA Safer Choice Certified, Plant-Powered – Free & Clear, 50 Fl Oz (Pack of 2)
Get clean clothes that are gentle on skin and the planet with ECOS Laundry Detergent Liquid! This pH-balanced formula is dermatologist-tested and hypoallergenic, making it perfect for sensitive skin.
ECOS is 100% vegan and cruelty-free, with a plant-powered formula that’s paraben and phosphate free. It’s made in the USA with globally sourced ingredients, so you can trust you’re getting a quality product.
Safer Choice certified, Black-owned, and woman-led, ECOS is a company that cares. Gently effective on clothes and the environment. Makes a difference with every load.
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Perfect For:
This ECOS Laundry Detergent is perfect for anyone seeking a gentle, effective, and eco-friendly way to clean their clothes. It’s ideal for families with sensitive skin and those who prioritize sustainable, plant-powered products.
Ready to Purchase?
2. Molly’s Suds Liquid Laundry Detergent | Clean Laundry Detergent Soap for Sensitive Skin | 2x Concentrated, High Efficiency (HE) | Peppermint – 100 Loads
Molly’s Suds Liquid Laundry Detergent cleans clothes gently. It is safe for sensitive skin.
It uses plant‑based surfactants and active enzymes to lift dirt. The peppermint essential oil scent is natural and fragrance‑free. It works well in hard water and HE machines.
One 52 oz bottle washes 100 loads. The formula is cruelty‑free and made in the USA. It is septic safe and saves water.
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Perfect For:
This Molly’s Suds Liquid Laundry Detergent is perfect for families and anyone with sensitive skin. Its simple, plant-based ingredients are tough on stains but gentle enough for eczema and allergies, making laundry day a breeze for everyone.
Ready to Purchase?
3. ECOS Laundry Detergent Liquid, 100 Loads – Dermatologist Tested Laundry Soap – Hypoallergenic, EPA Safer Choice Certified, Plant-Powered – Magnolia Lily, 50 Fl Oz (Pack of 2)
ECOS Laundry Detergent is a plant-powered and sustainable choice for your laundry needs. It’s pH-balanced and kind to sensitive skin, making it perfect for families.
This vegan and cruelty-free detergent is free from harsh chemicals like parabens and phosphates. It’s dermatologist-tested and hypoallergenic, ensuring a gentle clean for your clothes.
Made in the USA, Black-owned, and woman-led, ECOS uses 100% renewable energy and clean formulas for visible results.
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Perfect For:
This ECOS Laundry Detergent is perfect for families and individuals who want a powerful yet gentle clean for their clothes. It’s ideal for those with sensitive skin or allergies, as it’s dermatologist-tested and hypoallergenic. Plus, if you care about the environment and ethical choices, this vegan, cruelty-free, and EPA Safer Choice certified detergent is a fantastic option!
Ready to Purchase?
4. ARM & HAMMER Clean & Simple, 77 Loads Liquid Laundry Detergent, 100.5 Fl oz
Clean clothes, no fuss. ARM & HAMMER Clean & Simple tackles tough stains with 3X the power of basic detergents. Every drop works hard—without extra chemicals or dyes.
Baking Soda lifts dirt and odors while softening water for a deeper clean. It’s powerful yet gentle, free of phosphates, GMOs, parabens, and brighteners. Safe for you, your family, and the planet.
Works in any machine, any temperature. Great in cold water and safe for septic systems. Trust the same reliable clean—now with a fresh look. Laundry just got simpler.
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Perfect For:
This ARM & HAMMER Clean & Simple Laundry Detergent is perfect for anyone seeking a powerful yet gentle clean for their clothes. It’s ideal for those who want a deep clean without harsh chemicals, making it a smart choice for families and the environment.
Ready to Purchase?
5. Gain Liquid Laundry Detergent, Original Scent, 65 fl oz x 2, 45 x 2 Loads, Freshness + Odor Fighting, High Efficiency Washing Machine Liquid Cleaning Soap
Gain Liquid Laundry Detergent makes laundry easy. It has a long-lasting freshness that keeps your clothes smelling great. The original scent adds a nice touch to your laundry routine.
This detergent fights odors and cleans well. It works in any washing machine and at any water temperature. Enjoy a scent explosion by mixing it with other Gain products.
You get two bottles, each with 65 fl oz. That’s enough for 90 loads of laundry.
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Perfect For:
This Gain Liquid Laundry Detergent is perfect for anyone who wants long-lasting freshness and a powerful clean for their clothes. If you love a classic, clean scent and need a detergent that fights odors while being safe for all machines and water temperatures, this is your go-to!
Ready to Purchase?
6. ECOS® Hypoallergenic Laundry Detergent, Lavender, 200 loads, 100oz Bottle by Earth Friendly Products (Pack of 2)
The ECOS® Hypoallergenic Laundry Detergent with lavender scent is a powerful cleaner made from plant-derived ingredients. It comes in a 100oz bottle that provides up to 200 loads of laundry, making it a great choice for your family’s needs.
This detergent is 100% vegan and contains no harsh chemicals. It is dermatologist-tested and safe for sensitive skin. Enjoy the fresh scent of coconut and lavender essential oil with every wash.
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Perfect For:
This ECOS® Hypoallergenic Laundry Detergent is perfect for anyone who wants a gentle, plant-based clean. It’s great for sensitive skin and safe for the whole family.
Ready to Purchase?
7. ECOS Laundry Detergent Liquid, 100 Loads – Dermatologist Tested Laundry Soap – Hypoallergenic, EPA Safer Choice Certified, Plant-Powered – Magnolia Lily, 100 Fl Oz
Get ready for brilliantly clean clothes with ECOS Laundry Detergent in the delightful Magnolia Lily scent! This 100 load liquid detergent is dermatologist-tested and hypoallergenic, making it a dream for even the most sensitive skin.
It’s 100% vegan and cruelty-free. This detergent is paraben and phosphate-free. You’ll get visible results with every wash.
Made with plant-powered ingredients, this detergent is climate-positive and sustainable. ECOS is committed to safer, powerful products for your home and the planet.
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Perfect For:
ECOS Laundry Detergent is perfect for families who want a gentle, effective, and eco-friendly laundry solution. It’s ideal for sensitive skin and planet-conscious homes.
Ready to Purchase?
Buying Guide
Choosing the best 52-ounce laundry detergent for 100 loads is easy with the right guide. Let’s find the perfect one for you!
Factors to Consider When Buying:
– Cleaning Power: Look for detergents that tackle tough stains and dirt effectively. Check for plant-powered or enzyme-based formulas for a deep clean.
– Skin Sensitivity: Choose hypoallergenic and dermatologist-tested options if you have sensitive skin. Avoid harsh chemicals like parabens and phosphates.
– Scent: Decide if you want a fresh scent or a fragrance-free option. Natural scents like lavender or peppermint are great choices.
– Eco-Friendliness: Opt for vegan, cruelty-free, and EPA Safer Choice Certified products. These are kind to the planet and your home.
– Machine Compatibility: Ensure the detergent works in HE machines and hard water. Check if it’s septic safe for easy use.
– Concentration: 2x concentrated formulas save space and last longer. They’re also better for the environment.
– Brand Values: Support brands that align with your values, like Black-owned or woman-led companies.
With these tips, you’ll find a detergent that cleans well, cares for your skin, and helps the planet. Happy washing!