10 Best Enzyme Detergents for Spotless Laundry

Are you curious about the best enzyme detergents? Discover the top picks that real users love for tackling stains and keeping clothes fresh.

Enzyme detergents use natural power to fight stains and odors. They work with your regular wash for better results. Many are safe for pets and families.

People love how these detergents keep clothes fresh from pet messes. Real users say one scoop turns dirty laundry into clean bliss.

Trust our guide to find the top enzyme picks that fit your needs. Dive in to learn secrets for spotless washes that save time and money.

List of Top 10 Enzyme Detergents

Image Title Best For Price
Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads Enzyme Laundry Booster Odor Remover – 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood – 64 Loads

This laundry booster is perfect for busy families with dirty clothes from kids, meals, or workouts. It’s ideal for athletes who need to remove sweat, stains, and odors without harsh chemicals.

Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines

This laundry boost is perfect for pet owners who fight tough pet messes like urine or vomit on clothes and beds. It works in all machines and keeps your home fresh and safe for pets, no worries about harsh chemicals.

Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator - 64 Loads Pet Laundry Detergent Odor Remover – ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator – 64 Loads

This product is perfect for anyone with pets. It is great for removing stains and smells from pet items.

LaundraPet 3X Strength Premium Laundry Detergent with Enzyme Cleaner - 64 Oz (96 Washes) Pet Stain and Odor Eliminator, Enzymatic Detergent by Alpha Tech Pet LaundraPet 3X Strength Premium Laundry Detergent with Enzyme Cleaner – 64 Oz (96 Washes) Pet Stain and Odor Eliminator, Enzymatic Detergent by Alpha Tech Pet

This product is perfect for pet owners. It’s also great for groomers and vets.

Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High Efficiency & Standard Machine Washer | Nontoxic, Biodegradable | Stain & Odor Removal Enzyme Booster Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High Efficiency & Standard Machine Washer | Nontoxic, Biodegradable | Stain & Odor Removal Enzyme Booster

This laundry booster is great for people who want clean clothes. It is also perfect for those who care about the environment and sensitive skin.

Active Wear Laundry Detergent & Soak - Formulated for Sweat and Workout Clothes - Natural Performance Concentrate Enzyme Booster Deodorizer - Powder Wash for Activewear Gym Apparel (90 Loads) Active Wear Laundry Detergent & Soak – Formulated for Sweat and Workout Clothes – Natural Performance Concentrate Enzyme Booster Deodorizer – Powder Wash for Activewear Gym Apparel (90 Loads)

Are you tired of your workout clothes smelling funky? Are you ready to kick those lingering odors to the curb? This Active Wear Laundry Detergent & Soak is perfect for athletes, gym-goers, and anyone who works up a sweat. It’s time to say goodbye to smelly clothes and hello to fresh, clean activewear!

Dirty Labs | Scent Free | Bio Enzyme Liquid Laundry Detergent | 80 Loads (21.6 fl oz) | Hyper-Concentrated | High Efficiency & Standard Machine Washing | Nontoxic, Biodegradable | Stain & Odor Removal Dirty Labs | Scent Free | Bio Enzyme Liquid Laundry Detergent | 80 Loads (21.6 fl oz) | Hyper-Concentrated | High Efficiency & Standard Machine Washing | Nontoxic, Biodegradable | Stain & Odor Removal

This laundry detergent is perfect for people with sensitive skin, babies, and pets because it’s gentle and safe to use. It’s also ideal for eco-conscious shoppers who want an effective, biodegradable cleaner that fights stains and odors without harmful chemicals.

Pro-Enzyme Laundry Detergent Powder, Non-Irritating Professional Strength Natural Active Enzymes - Powerful Sweat, Odor & Stain Remover for Activewear, Clothing, Bedding, Use in All Machines, 96 Loads Pro-Enzyme Laundry Detergent Powder, Non-Irritating Professional Strength Natural Active Enzymes – Powerful Sweat, Odor & Stain Remover for Activewear, Clothing, Bedding, Use in All Machines, 96 Loads

This Pro-Enzyme Laundry Detergent Powder is perfect for active people. It’s great for anyone who wants clean, fresh-smelling clothes!

Puracy Laundry Detergent - Enzyme-Powered Liquid Laundry Detergent Concentrate, Natural Laundry Detergent Seen on TikTok, Non-Toxic (Fresh Linen, 16 fl oz, 64 Loads) Puracy Laundry Detergent – Enzyme-Powered Liquid Laundry Detergent Concentrate, Natural Laundry Detergent Seen on TikTok, Non-Toxic (Fresh Linen, 16 fl oz, 64 Loads)

This laundry detergent is perfect for everyone. It is especially great for people with sensitive skin.

Lazy Coconuts Complete 5 Enzyme Laundry Detergent Strips - Unscented, 48 Loads - Sulfate Free Laundry Detergent With Solid And Liquid Enzymes - Fights Natural Stains and Odor Lazy Coconuts Complete 5 Enzyme Laundry Detergent Strips – Unscented, 48 Loads – Sulfate Free Laundry Detergent With Solid And Liquid Enzymes – Fights Natural Stains and Odor

This natural detergent is perfect for eco-conscious families who want a simple, green way to clean clothes without harmful chemicals. It’s also ideal for people with sensitive skin seeking an easy, mess-free laundry option that fights stains and smells.

Detailed Reviews

Our expert analysis and customer feedback have pinpointed the top 10 Enzyme Detergents that shine in stain removal and odor control. Each one is thoroughly reviewed to show its unique features, solid performance, and great value, giving you the confidence to choose wisely. Dive into our guide to find the perfect match for your laundry needs, whether you’re after comfort or just want something affordable. With clear comparisons and tips, we’re here to make your decision a breeze and leave your clothes smelling fresh.

1. Enzyme Laundry Booster Odor Remover – 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood – 64 Loads

Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

Tired of stubborn stains and lingering odors? This Enzyme Laundry Booster is your answer. It’s a powerful cleaner that works with your regular detergent. Say goodbye to unwanted smells!

This product is safe for all fabrics and washers. You get a 64-load package for great value.

Pros Cons
  • Eliminates stubborn odors and tough stains effectively.
  • Gentle formula safe for all fabrics and colors.
  • Boosts laundry power with 64 loads per package.
  • Works with any washer or detergent perfectly.
  • Natural enzymes target grease, sweat, and oil.
  • Unscented powder offers no fresh smell.
  • Seemingly makes some washers messier.
  • Convenient but needs extra storage space.

Perfect For:

This laundry booster is perfect for busy families with dirty clothes from kids, meals, or workouts. It’s ideal for athletes who need to remove sweat, stains, and odors without harsh chemicals.

Ready to Purchase?

2. Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines

Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Ounces, Laundry Stain and Odor Removing Additive For All Machines

This Nature’s Miracle Laundry Boost fights tough pet stains and odors like urine and grass in your wash. Its bio-enzymatic formula breaks down messes so clothes come out clean and fresh.
Safe for pets and homes, it works in all washing machines without harsh chemicals. Add it to your laundry to boost your detergent’s power. Try it today to make chores easier.

Pros Cons
  • Breaks down tough pet stains and odors.
  • Gentle on most fabrics and pet beds.
  • Safe for pets and your home.
  • Neutralizes odors with advanced technology.
  • Works in all washing machines easily.
  • Skips delicate fabrics like silk.
  • Works best on pet stains only.
  • Needs detergent to clean well.

Perfect For:

This laundry boost is perfect for pet owners who fight tough pet messes like urine or vomit on clothes and beds. It works in all machines and keeps your home fresh and safe for pets, no worries about harsh chemicals.

Ready to Purchase?

3. Pet Laundry Detergent Odor Remover – ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator – 64 Loads

Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural Enzymatic Deodorizer, Urine, Smell, Dog Drool, Stain Eliminator - 64 Loads

Keep your home fresh with ACTIVE Pet Laundry Detergent! This powerful detergent removes tough stains and odors.

It is safe for all pet items, like beds and clothes. The natural enzymes get rid of smells from pets. This detergent is also safe for your own clothes.

You get a lot of washes in one bag. It is easy to use: just add a scoop to your machine. It is a great value.

Pros Cons
  • Powerful stain and odor removal for pet laundry.
  • Safe for all fabric types, even your clothes!
  • Natural and fragrance-free for sensitive pets.
  • 64 loads in one cost-effective package!
  • Easy-to-use with simple washing instructions.
  • Powder form might leave residue if not dissolved well.
  • Needs pre-soaking for strong odors, taking more time.
  • Fragrance-free, but it may lack a fresh scent some prefer.

Perfect For:

This product is perfect for anyone with pets. It is great for removing stains and smells from pet items.

Ready to Purchase?

4. LaundraPet 3X Strength Premium Laundry Detergent with Enzyme Cleaner – 64 Oz (96 Washes) Pet Stain and Odor Eliminator, Enzymatic Detergent by Alpha Tech Pet

LaundraPet 3X Strength Premium Laundry Detergent with Enzyme Cleaner - 64 Oz (96 Washes) Pet Stain and Odor Eliminator, Enzymatic Detergent by Alpha Tech Pet

Say goodbye to stubborn pet stains and odors. LaundraPet tackles everything from urine and poop messes to heavy dirt on clothes.

Its triple-action enzymes boost cleaning power by 15% for brighter results. You can wash in cold water to save energy. Plus, it removes odors that linger on fabrics.

This detergent is vet-approved and safe for pets and families. It’s eco-friendly and made in the USA. Trust a brand with 38 years of caring for animal needs.

Pros Cons
  • Eradicates tough pet stains and odors effectively.
  • Triple-action enzymes deliver powerful cleaning.
  • Safe for pets, family, and the environment.
  • Perfect for HE washers, saving money.
  • Trusted by vets with 38+ years experience.
  • May not remove all stains.
  • Requires following wash instructions.
  • Scent may not suit everyone.

Perfect For:

This product is perfect for pet owners. It’s also great for groomers and vets.

Ready to Purchase?

5. Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High Efficiency & Standard Machine Washer | Nontoxic, Biodegradable | Stain & Odor Removal Enzyme Booster

Dirty Labs | Scent Free | Bio Enzyme Laundry Booster | 48 Loads (1 lb) | Hyper Concentrated | High Efficiency & Standard Machine Washer | Nontoxic, Biodegradable | Stain & Odor Removal Enzyme Booster

Transform your laundry routine with Dirty Labs Scent Free Bio Enzyme Laundry Booster. This powerful, hyper-concentrated formula tackles tough stains and odors without harsh chemicals. You can trust that it keeps both your clothes and the planet clean.

Get incredible results with just one scoop. It breaks down sweat, grime, and even blood stains. Safe for all washers, it’s perfect for the whole family.

Choose safety and effectiveness with every wash. Our nontoxic, biodegradable ingredients ensure that everyone—humans, pets, and the earth—stays protected. Make laundry day simpler and brighter with Dirty Labs.

Pros Cons
  • Breaks down tough stains from sweat and grime easily.
  • Safe for babies and pets with gentle, nontoxic ingredients.
  • Cuts waste and carbon footprint as hyper-concentrated formula.
  • Recyclable packaging keeps it natural and green.
  • Works in all washers for quick, effective clean.
  • Limited to 48 loads per container.
  • Requires using laundry detergent.
  • Price might be higher than some alternatives.

Perfect For:

This laundry booster is great for people who want clean clothes. It is also perfect for those who care about the environment and sensitive skin.

Ready to Purchase?

6. Active Wear Laundry Detergent & Soak – Formulated for Sweat and Workout Clothes – Natural Performance Concentrate Enzyme Booster Deodorizer – Powder Wash for Activewear Gym Apparel (90 Loads)

Active Wear Laundry Detergent & Soak - Formulated for Sweat and Workout Clothes - Natural Performance Concentrate Enzyme Booster Deodorizer - Powder Wash for Activewear Gym Apparel (90 Loads)

Tired of smelly workout clothes? ACTIVE is the answer! This natural detergent is made for your activewear. It removes odors and keeps your clothes fresh.

ACTIVE is easy to use and saves you money. It’s a plant-based formula with 90 loads per bag. Get yours today!

Pros Cons
  • Removes sweat odors from workout clothes naturally.
  • Extends clothes lifespan for lasting wear.
  • Plant-based enzymes keep it safe and septic friendly.
  • Concentrated formula gives 90 loads at great value.
  • Made in USA with specialized activewear care.
  • Powder form may stick to clothes if not rinsed well.
  • Concentrated mix needs careful measuring to avoid waste.
  • Bulk bag can be messy when pouring.

Perfect For:

Are you tired of your workout clothes smelling funky? Are you ready to kick those lingering odors to the curb? This Active Wear Laundry Detergent & Soak is perfect for athletes, gym-goers, and anyone who works up a sweat. It’s time to say goodbye to smelly clothes and hello to fresh, clean activewear!

Ready to Purchase?

7. Dirty Labs | Scent Free | Bio Enzyme Liquid Laundry Detergent | 80 Loads (21.6 fl oz) | Hyper-Concentrated | High Efficiency & Standard Machine Washing | Nontoxic, Biodegradable | Stain & Odor Removal

Dirty Labs | Scent Free | Bio Enzyme Liquid Laundry Detergent | 80 Loads (21.6 fl oz) | Hyper-Concentrated | High Efficiency & Standard Machine Washing | Nontoxic, Biodegradable | Stain & Odor Removal

Dirty Labs makes a scent-free bio enzyme liquid laundry detergent that cleans 80 loads from a small 21.6 fl oz bottle. It uses safe, nontoxic ingredients to remove stains and odors without harming your skin, pets, or the planet.
Our hyper-concentrated formula works great in both high-efficiency and standard washers. It packs advanced enzymes that fight dirt deeply while being kind to fabrics. Plus, it’s biodegradable and comes in a recyclable aluminum bottle.

Pros Cons
  • Gentle on sensitive skin and fabrics.
  • Powerful stain and odor removal.
  • Eco-friendly with recyclable packaging.
  • Safe for babies and pets.
  • Concentrated for 80 loads per bottle.
  • Hyper-concentrated calls for small amounts that need careful measuring.
  • Aluminum bottle may dent or crush easily during storage.
  • Pretreatment takes 5 minutes wait time for tough stains.

Perfect For:

This laundry detergent is perfect for people with sensitive skin, babies, and pets because it’s gentle and safe to use. It’s also ideal for eco-conscious shoppers who want an effective, biodegradable cleaner that fights stains and odors without harmful chemicals.

Ready to Purchase?

8. Pro-Enzyme Laundry Detergent Powder, Non-Irritating Professional Strength Natural Active Enzymes – Powerful Sweat, Odor & Stain Remover for Activewear, Clothing, Bedding, Use in All Machines, 96 Loads

Pro-Enzyme Laundry Detergent Powder, Non-Irritating Professional Strength Natural Active Enzymes - Powerful Sweat, Odor & Stain Remover for Activewear, Clothing, Bedding, Use in All Machines, 96 Loads

Say goodbye to gym odors with our Pro-Enzyme Laundry Detergent Powder. It uses natural enzymes to clean activewear like shirts, shorts, and leggings. This eco-friendly formula is safe for all machines and keeps clothes fresh without harsh chemicals.

Revive your fabrics and eliminate tough stains in one wash. Our concentrated detergent works well on whites, colors, and bedding. It stays gentle on clothes while providing powerful cleaning that lasts for over 90 loads.

Enjoy complete peace of mind with our 100% satisfaction guarantee. If you love it, great; if not, contact us for a fix.

Pros Cons
  • Natural enzymes blast away sweat odors in activewear.
  • Gentle formula revives fabrics without damage.
  • Powerful ingredients tackle tough stains and soils.
  • Eliminates odors at the source for fresh clothes.
  • Concentrated power lasts over 90 loads economically.
  • Messy powder scatters easily.
  • Higher cost than basic brands.
  • Needs careful measuring for loads.

Perfect For:

This Pro-Enzyme Laundry Detergent Powder is perfect for active people. It’s great for anyone who wants clean, fresh-smelling clothes!

Ready to Purchase?

9. Puracy Laundry Detergent – Enzyme-Powered Liquid Laundry Detergent Concentrate, Natural Laundry Detergent Seen on TikTok, Non-Toxic (Fresh Linen, 16 fl oz, 64 Loads)

Puracy Laundry Detergent - Enzyme-Powered Liquid Laundry Detergent Concentrate, Natural Laundry Detergent Seen on TikTok, Non-Toxic (Fresh Linen, 16 fl oz, 64 Loads)

Get clean clothes with Puracy Laundry Detergent. It uses natural ingredients. This detergent is safe for sensitive skin.

This detergent is made by doctors and scientists. It is also safe for the environment.

Pros Cons
  • Clean, fresh laundry minus irritating residues.
  • Gentle on sensitive skin, zero sulfates.
  • 99% plant-powered, safe for all fabrics.
  • Eco-friendly use cuts waste effectively.
  • Made in USA, never tested on animals.
  • May need extra doses for really dirty clothes.
  • Subtle scent lacks strong perfume punch.
  • Concentrate could mean measuring mistakes or waste.

Perfect For:

This laundry detergent is perfect for everyone. It is especially great for people with sensitive skin.

Ready to Purchase?

10. Lazy Coconuts Complete 5 Enzyme Laundry Detergent Strips – Unscented, 48 Loads – Sulfate Free Laundry Detergent With Solid And Liquid Enzymes – Fights Natural Stains and Odor

Lazy Coconuts Complete 5 Enzyme Laundry Detergent Strips - Unscented, 48 Loads - Sulfate Free Laundry Detergent With Solid And Liquid Enzymes - Fights Natural Stains and Odor

Lazy Coconuts Complete 5 Enzyme Laundry Detergent Strips cut through tough stains and odors with a powerful mix of lipase, mannase, protease, amylase, and cellulase enzymes.

These unscented strips keep your laundry safe and clean, without harsh chemicals, for a fresh, pure feel.
They’re plastic-free and come in recyclable packaging, helping the planet with carbon negative certification that offsets emissions twice over.
Grab a box of 48 easy strips for mess-free washing that saves time and space.

Pros Cons
  • Complete cleaning with a 5-enzyme formula.
  • Free of harsh chemicals for gentle cleaning.
  • Plastic-free and eco-friendly for a sustainable choice.
  • Easy-to-use pre-measured strips for convenience.
  • Carbon Negative for a cleaner planet.
  • Might need two strips for large or heavily soiled loads.
  • Enzyme formulas may not suit all delicate fabrics.
  • New laundry strip users may need to adjust dosage.

Perfect For:

This natural detergent is perfect for eco-conscious families who want a simple, green way to clean clothes without harmful chemicals. It’s also ideal for people with sensitive skin seeking an easy, mess-free laundry option that fights stains and smells.

Ready to Purchase?

Buying Guide

Enzyme detergents clean clothes with natural power. They fight tough stains and odors without extra effort.

Real users share how these detergents change laundry time. One user cleaned dog pee stains from a sofa with a scoop of powder. The smell vanished after one wash. Another said gym clothes stayed fresh for weeks. Families love pet-safe options that keep homes odor-free.

  • Product Type: Choose between powder, liquid, or strips based on ease. Powders mix well in all washers. Liquids pour easily for quick use.
  • Enzyme Strength: Pick detergents with strong enzymes like protease or lipase. They break down proteins and fats in stains. This gives deeper cleaning power.
  • Scent Options: Go for unscented or light smells if you want no fragrance. Many products offer odor removal without new smells. This suits sensitive people and pets.
  • Pet-Friendly Features: Select ones safe for pets and their items. These handle urine and drool messes. They keep pet beds and clothes clean without harm.
  • Load Capacity: Check the number of washes per package. Bigger sizes like 96 loads save money. Smaller ones test quality first.
  • Wash Compatibility: Ensure it fits your washer type. Most work in high-efficiency or standard machines. Some even soak clothes for extra clean.
  • Eco-Friendly Choices: Look for biodegradable and nontoxic options. They use safe ingredients. This protects the planet and your health.
  • Price and Value: Compare costs per load for deals. Vet-approved brands may cost more. Brands with guarantees offer peace of mind.
  • Fabric Safety: Verify it works on all fabrics and colors. Gentle formulas prevent fading. They clean whites and darks alike.
  • Odor Removal: Focus on products that eliminate sweat or food smells. Enzymes target root causes. Clothes stay fresh longer after washing.
  • Brand Reputation: Choose trusted makers with good reviews. Long-time pet care companies build trust. User stories highlight real results.