Looking for the best hypoallergenic laundry detergent for eczema? We’ve curated a list of 10 top options to help you find the perfect match for clean clothes and happy skin.
Eczema can make laundry day tricky. Choosing the right detergent is key to keeping skin calm. This guide helps you find the best hypoallergenic option.
Gentle formulas protect sensitive skin. No harsh chemicals means less irritation. We’ve tested top brands for you.
Discover eczema-friendly detergents that work. Clean clothes, happy skin—it’s possible. Let’s dive in and find your perfect match.
List of Top 10 Hypoallergenic Laundry Detergent For Eczema
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ARM & HAMMER Sensitive Skin Free & Clear Liquid Laundry Detergent, 105 fl oz, 105 Loads |
This ARM & HAMMER detergent is perfect for families who want a gentle, yet powerful clean. It’s ideal for sensitive skin and tough on stains, making laundry day easy and worry-free. |
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ARM & HAMMER Sensitive Skin Free & Clear, 140 Loads Liquid Laundry Detergent, 140 Fl oz |
This ARM & HAMMER detergent is perfect for families who want gentle, effective cleaning. It’s great for sensitive skin and tough on stains. |
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all free clear, Original, Liquid Laundry Detergent for Sensitive Skin, Unscented and Hypoallergenic, Concentrated, 82.5oz, 110 Loads |
This detergent is perfect for families with sensitive skin. It’s gentle, hypoallergenic, and free of perfumes and dyes. |
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Tide Free & Gentle Liquid Laundry Detergent, 100 Loads, 132 fl oz, Tide Laundry Detergent, Clean Laundry Detergent |
Tide Free & Gentle is perfect for families who want a deep clean without irritating skin. It’s great for sensitive skin and removes tough stains easily. |
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ARM & HAMMER Sensitive Skin Free Clear, 170 Loads Liquid Laundry Detergent, 170 Fl oz |
This ARM & HAMMER detergent is perfect for families who want a gentle, effective clean. It’s great for sensitive skin and tough on stains, making laundry easy and worry-free. |
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Dreft Free & Gentle Liquid Laundry Detergent, Free of Dyes and Perfumes for Families, Hypoallergenic, 64 loads |
This detergent is perfect for newborns, sensitive skin, and families who want a safe, effective clean without harsh additives. Pediatricians recommend it because it’s tough on messes but gentle from the first wash—no perfumes, no dyes, just pure care for delicate skin. Parents trust Dreft’s 80-year legacy to protect what matters most: baby’s soft clothes and peace of mind. Ideal for everyday laundry, it meets strict safety standards so you can wash confidently, load after load. |
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Seventh Generation Laundry Detergent Packs, Free & Clear, Made for Sensitive Skin, EPA Safer Choice Certified, 64 Count |
Seventh Generation Laundry Detergent Packs are perfect for families with sensitive skin. They’re free of fragrances and dyes, hypoallergenic, and safe for everyone. |
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Seventh Generation Concentrated Laundry Detergent Liquid Free & Clear Fragrance Free 40 oz |
This detergent is perfect for families with sensitive skin or allergies. It’s also great for anyone who loves plant-based and eco-friendly products. |
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ECOS Laundry Detergent Liquid, 200 Loads – Dermatologist Tested Laundry Soap – Hypoallergenic, EPA Safer Choice Certified, Plant-Powered – Lavender, 100 Fl Oz (Pack of 2) |
ECOS Laundry Detergent is perfect for families who want a gentle, effective, and eco-friendly laundry solution. It’s ideal for sensitive skin and planet-conscious homes. |
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ECOS Laundry Detergent Liquid, 100 Loads – Dermatologist Tested Laundry Soap – Hypoallergenic, EPA Safer Choice Certified, Plant-Powered – Free & Clear, 50 Fl Oz (Pack of 2) |
ECOS Laundry Detergent is perfect for families who want a gentle, effective, and eco-friendly laundry solution. It’s ideal for sensitive skin and planet-conscious households. |
Detailed Reviews
We tested and analyzed customer reviews and expert insights to identify the best hypoallergenic laundry detergents for eczema. Each product delivers gentle, residue-free cleaning proven safe for sensitive and eczema-prone skin. Trusted certifications like SkinSAFE, NEA, and EPA Safer Choice back their formulations. Discover which ones truly protect skin while removing stains—keep reading for clear, reliable guidance.
1. ARM & HAMMER Sensitive Skin Free & Clear Liquid Laundry Detergent, 105 fl oz, 105 Loads

ARM & HAMMER Sensitive Skin Free & Clear Liquid Laundry Detergent is gentle on skin but tough on stains. One 105 fl oz bottle cleans 105 loads of laundry. It’s dye-free and perfume-free, perfect for sensitive skin.
This dermatologist-tested detergent is hypoallergenic and certified 100% by SkinSAFE. It excludes top skin allergens, so you can trust it for your family.
With ARM & HAMMER Baking Soda, it deeply cleans clothes while being kind to skin. It’s 2X more powerful than leading value detergents, making it efficient and effective.
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Perfect For:
This ARM & HAMMER detergent is perfect for families who want a gentle, yet powerful clean. It’s ideal for sensitive skin and tough on stains, making laundry day easy and worry-free.
Ready to Purchase?
2. ARM & HAMMER Sensitive Skin Free & Clear, 140 Loads Liquid Laundry Detergent, 140 Fl oz

ARM & HAMMER Sensitive Skin Free & Clear is a gentle yet powerful laundry detergent. It comes in a 140 fl oz bottle, enough for 140 medium loads. This detergent is dermatologist-tested and hypoallergenic, making it perfect for sensitive skin.
The formula is free from dyes, perfumes, and preservatives. It’s certified 100% by SkinSAFE, ensuring it excludes top skin allergens. With ARM & HAMMER Baking Soda, it deeply cleans clothes while being kind to your skin.
This HE detergent is concentrated with 2X stain fighters. It’s an effective and efficient choice for your laundry needs. Clean Deep, Don’t Spend Deep – a trusted household staple for generations.
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Perfect For:
This ARM & HAMMER detergent is perfect for families who want gentle, effective cleaning. It’s great for sensitive skin and tough on stains.
Ready to Purchase?
3. all free clear, Original, Liquid Laundry Detergent for Sensitive Skin, Unscented and Hypoallergenic, Concentrated, 82.5oz, 110 Loads

All Free Clear is the #1 recommended laundry detergent for sensitive skin. It’s 100% free of perfumes and dyes, making it gentle yet effective. Perfect for families, it’s trusted by experts.
This concentrated formula packs more cleaning power per drop. It removes impurities like dirt and allergens without leaving residues. Works great in cold water and HE machines.
Safer Choice certified, it’s better for your family and the planet. Includes biodegradable surfactants and is septic-safe. One bottle lasts for 110 loads.
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Perfect For:
This detergent is perfect for families with sensitive skin. It’s gentle, hypoallergenic, and free of perfumes and dyes.
Ready to Purchase?
4. Tide Free & Gentle Liquid Laundry Detergent, 100 Loads, 132 fl oz, Tide Laundry Detergent, Clean Laundry Detergent

Tide Free & Gentle is a powerful yet gentle laundry detergent. It removes tough stains while being kind to sensitive skin. Perfect for families who need a reliable clean.
This detergent is trusted by experts. It’s NEA, EPA Safer Choice, and NPF Certified. No perfumes, dyes, or irritating residues make it hypoallergenic.
Use it in any washing machine and any water condition. It works on 100% of common stains and is safe for all fabrics. One bottle handles 100 loads with ease.
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Perfect For:
Tide Free & Gentle is perfect for families who want a deep clean without irritating skin. It’s great for sensitive skin and removes tough stains easily.
Ready to Purchase?
5. ARM & HAMMER Sensitive Skin Free Clear, 170 Loads Liquid Laundry Detergent, 170 Fl oz

Gentle on skin, powerful on stains. This dermatologist-tested, hypoallergenic liquid cleans 170 loads with no perfumes, dyes, or preservatives—certified 100% safe for sensitive skin by SkinSAFE.
Trusted baking soda lifts dirt and odors without irritation. Concentrated formula works in all machines, especially HE. Saves money while delivering deep clean.
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Perfect For:
This ARM & HAMMER detergent is perfect for families who want a gentle, effective clean. It’s great for sensitive skin and tough on stains, making laundry easy and worry-free.
Ready to Purchase?
6. Dreft Free & Gentle Liquid Laundry Detergent, Free of Dyes and Perfumes for Families, Hypoallergenic, 64 loads

Dreft Free & Gentle Liquid Laundry Detergent is pediatrician-recommended for baby’s delicate skin. It’s hypoallergenic, with no dyes or perfumes, making it safe for sensitive skin. This detergent is tough on stains but gentle on fabrics.
It meets EPA Safe Choice and NEA standards, ensuring a safe and effective clean. With 80 years of trust, Dreft is a reliable choice for your family’s laundry needs.
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Perfect For:
This detergent is perfect for newborns, sensitive skin, and families who want a safe, effective clean without harsh additives.
Pediatricians recommend it because it’s tough on messes but gentle from the first wash—no perfumes, no dyes, just pure care for delicate skin.
Parents trust Dreft’s 80-year legacy to protect what matters most: baby’s soft clothes and peace of mind.
Ideal for everyday laundry, it meets strict safety standards so you can wash confidently, load after load.
Ready to Purchase?
7. Seventh Generation Laundry Detergent Packs, Free & Clear, Made for Sensitive Skin, EPA Safer Choice Certified, 64 Count

Seventh Generation Laundry Detergent Packs are made for sensitive skin. They are free from fragrances and dyes, making them gentle on your family.
These packs fight tough stains like chocolate, dirt, and grass. They dissolve in hot or cold water and are easy to use.
They are EPA Safer Choice Certified, the number 1 choice for safer laundry. These packs are hypoallergenic and safe for your family.
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Perfect For:
Seventh Generation Laundry Detergent Packs are perfect for families with sensitive skin. They’re free of fragrances and dyes, hypoallergenic, and safe for everyone.
Ready to Purchase?
8. Seventh Generation Concentrated Laundry Detergent Liquid Free & Clear Fragrance Free 40 oz

Seventh Generation laundry detergent is tough on stains but gentle on skin. Its triple-enzyme formula fights dirt without harsh chemicals. This fragrance-free detergent is perfect for sensitive skin.
It’s EPA Safer Choice Certified and USDA Certified Biobased, made with plant-based ingredients. One bottle washes 53 medium loads, working in HE or standard machines.
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Perfect For:
This detergent is perfect for families with sensitive skin or allergies. It’s also great for anyone who loves plant-based and eco-friendly products.
Ready to Purchase?
9. ECOS Laundry Detergent Liquid, 200 Loads – Dermatologist Tested Laundry Soap – Hypoallergenic, EPA Safer Choice Certified, Plant-Powered – Lavender, 100 Fl Oz (Pack of 2)

ECOS Laundry Detergent is a powerful and gentle cleaning solution. It’s safe for sensitive skin and the environment.
This detergent is 100% vegan and cruelty-free. It’s free from harsh chemicals like parabens and phosphates. ECOS is made in the USA with globally sourced ingredients.
The formula is dermatologist-tested and hypoallergenic. It’s certified as a safer choice for people and the planet. ECOS is a Black-owned and woman-led company.
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Perfect For:
ECOS Laundry Detergent is perfect for families who want a gentle, effective, and eco-friendly laundry solution. It’s ideal for sensitive skin and planet-conscious homes.
Ready to Purchase?
10. ECOS Laundry Detergent Liquid, 100 Loads – Dermatologist Tested Laundry Soap – Hypoallergenic, EPA Safer Choice Certified, Plant-Powered – Free & Clear, 50 Fl Oz (Pack of 2)

ECOS Laundry Detergent is a plant-powered and hypoallergenic solution for your laundry needs. It’s dermatologist-tested, making it gentle on sensitive skin.
This vegan and cruelty-free detergent is free from harsh chemicals like parabens and phosphates. It’s also EPA Safer Choice Certified, ensuring it’s safe for both people and the planet.
Made in the USA, Black-owned, and woman-led, ECOS delivers clean clothes with a clear conscience.
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Perfect For:
ECOS Laundry Detergent is perfect for families who want a gentle, effective, and eco-friendly laundry solution. It’s ideal for sensitive skin and planet-conscious households.
Ready to Purchase?
Buying Guide
Eczema makes laundry day tricky. Choosing the right detergent is key to calm skin. This guide helps you find the best hypoallergenic option.
Finding the perfect laundry detergent for eczema can feel like a challenge. But don’t worry, we’ve tested top brands to make it easy for you. Discover eczema-friendly detergents that keep clothes clean and skin happy.
Here’s what to consider when buying:
- Gentle Formulas: Look for detergents labeled hypoallergenic or dermatologist-tested. These are less likely to irritate sensitive skin.
- No Harsh Chemicals: Avoid dyes, perfumes, and preservatives. They can trigger eczema flare-ups.
- Certifications: Choose detergents certified by SkinSAFE or EPA Safer Choice. These meet strict safety standards.
- Concentrated Power: Opt for concentrated formulas for more cleaning power with less product. Saves money and space.
- Load Capacity: Check the number of loads per bottle. Larger sizes are cost-effective for big families.
- Machine Compatibility: Ensure the detergent works in HE machines if that’s what you use.
- Eco-Friendly: Pick plant-based or biodegradable options for a greener choice.
With these tips, you’ll find the perfect detergent for clean clothes and happy skin.