Looking for the best enzyme-based cleaners? Our guide features real user experiences and practical tips so you can confidently pick a cleaner that eliminates stains, odors, and pet accidents.
Enzyme cleaners work hard to remove stubborn stains and bad smells. People love them for pet accidents and dirty spots. One user shared how it erased her dog’s urine from the carpet in minutes.
Real users tell stories of clean homes without harsh chemicals. They feel confident using these on fabrics and floors. Trust our guide to pick the right cleaner for you.
Imagine a world with no strong odors. These cleaners keep working days after you apply them. Read on to find your perfect match.
List of Top 10 Enzyme-Based Cleaners
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Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon |
This Bioda Multi-Purpose Probiotic Enzyme Cleaner is perfect for anyone who wants an easy way to clean and deodorize their home. It is great for trash cans, pet messes, and more! |
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Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner – Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces – 32 Ounce – Fragrance Free |
This Zeiff Pro-Grade cleaner is perfect for anyone who wants a clean home or workspace. It’s great for professionals and people who want powerful cleaning results. |
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Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz |
This product is perfect for pet owners. It is designed for those who want to easily clean up stains and odors caused by their cats and dogs. |
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Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz |
This product is perfect for pet owners. It is for anyone who wants to easily clean up pet messes and keep their home smelling fresh and clean. |
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AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack |
This enzyme cleaner is perfect for business owners in hotels, restaurants, and stores who need to tackle stubborn stains and smells from pets, grease, and dirt. It works great for quick spot cleaning on carpets, toilets, and drains in busy commercial spaces. |
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Nature’s Miracle Urine Destroyer Plus Cat, 32 Ounces, Enzymatic Formula, Ready-to-Use |
This product is perfect for cat owners. It’s designed to remove stains and odors caused by cat urine. |
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Commercial Multi-Purpose Enzyme Cleaner & Odor Eliminator | Pet & Human Urine, Stains & Odors | Carpet, Laundry, Bathroom, Drain & Trash Deodorizer | Dog, Cat, Organic Waste Remover (1 Gallon) |
This cleaner is perfect for people with pets like dogs and cats, tackling stains, odors, and messes from urine or vomit. It also fits families who need a safe way to clean carpets, floors, and bathrooms. |
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Enzyme Laundry Booster Odor Remover – 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood – 64 Loads |
The Enzyme Laundry Booster Odor Remover is perfect for people who need to fight tough stains and strong smells on clothes, like sweat, oil, blood, and grease, without harsh chemicals. It’s great for families, athletes, and anyone who wants gentle, natural cleaning that works with any detergent and washer. |
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Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps | 1 Gallon |
This Green Gobbler product is perfect for anyone with clogged drains or smelly pipes. It’s also great for those who want to keep their septic tanks and grease traps working well. |
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Nature’s Miracle Urine Destroyer Plus Dog, 32 Ounces, Enzymatic Formula, Ready-to-Use |
This product is perfect for dog owners dealing with pesky urine messes in their homes. It helps clean up stains quickly and keeps things fresh for you and your pet. |
Detailed Reviews
Top enzyme cleaners shine through expert picks and real reviews for fresh homes. Find pro tips on powerful stains and nasty odors to match your clean needs. Dive in for trusted choices that work hard on everything from pet messes to daily grime.
1. Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon
Get ready to experience the cleaning power of Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer! This professional-strength cleaner tackles tough messes with ease. It’s perfect for your home or business.
This product is versatile. It works on many surfaces. The probiotics keep working for up to 21 days!
Bioda uses a special blend of enzymes. It gets rid of bad smells and leaves a fresh scent. It is made in the USA and comes in a 1-gallon bottle.
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Perfect For:
This Bioda Multi-Purpose Probiotic Enzyme Cleaner is perfect for anyone who wants an easy way to clean and deodorize their home. It is great for trash cans, pet messes, and more!
Ready to Purchase?
2. Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner – Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces – 32 Ounce – Fragrance Free
Get ready for Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner! It’s a powerful cleaner for your home and professional spaces. This product will give you pro-grade clean results.
This cleaner is safe and effective on many surfaces. It eliminates odors and breaks down tough stains. You’ll love the long-lasting freshness.
Zeiff is a multi-purpose cleaner. It is also made in the USA.
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Perfect For:
This Zeiff Pro-Grade cleaner is perfect for anyone who wants a clean home or workspace. It’s great for professionals and people who want powerful cleaning results.
Ready to Purchase?
3. Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz
Rocco & Roxie makes a strong enzyme cleaner. It removes bad smells from pets. It works on spots and stains.
Use it on carpets, floors, and beds. It fixes pee from cats and dogs.
You can trust this safe cleaner. No harmful stuff for pets or kids. Clean your home soon.
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Perfect For:
This product is perfect for pet owners. It is designed for those who want to easily clean up stains and odors caused by their cats and dogs.
Ready to Purchase?
4. Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz
Got pet messes? This urine destroyer is your new best friend!
It kills odors and removes stains from carpets and more. Pets won’t want to go to the same spot again. Use it safely around your furry friends.
| Pros | Cons |
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Perfect For:
This product is perfect for pet owners. It is for anyone who wants to easily clean up pet messes and keep their home smelling fresh and clean.
Ready to Purchase?
5. AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
Introducing the AmazonCommercial Multi-Purpose Enzyme Cleaner. This 1-gallon solution is perfect for many surfaces. It’s designed to tackle tough messes.
The cleaner breaks down pet odors, stains, and even grease. It works well in places like commercial properties and hotels.
Use it anytime for spot cleaning carpets, surfaces, and drains. Enjoy a fresh and clean environment with ease.
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Perfect For:
This enzyme cleaner is perfect for business owners in hotels, restaurants, and stores who need to tackle stubborn stains and smells from pets, grease, and dirt. It works great for quick spot cleaning on carpets, toilets, and drains in busy commercial spaces.
Ready to Purchase?
6. Nature’s Miracle Urine Destroyer Plus Cat, 32 Ounces, Enzymatic Formula, Ready-to-Use
Tackle those stubborn cat urine messes with Nature’s Miracle Urine Destroyer Plus. It uses a powerful enzymatic formula to break down stains and remove odors right away.
Soak the spot for 15 minutes. Blot up the mess with a clean cloth. The enzymes keep working on the stain as long as it’s there.
Trust this formula from the Nature’s Miracle brand – it always works. It’s safe for pets and your home when used correctly. Grab a bottle now and say goodbye to cat urine problems!
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Perfect For:
This product is perfect for cat owners. It’s designed to remove stains and odors caused by cat urine.
Ready to Purchase?
7. Commercial Multi-Purpose Enzyme Cleaner & Odor Eliminator | Pet & Human Urine, Stains & Odors | Carpet, Laundry, Bathroom, Drain & Trash Deodorizer | Dog, Cat, Organic Waste Remover (1 Gallon)
Powerful enzymatic action breaks down stains and odors at the source. It fights pet accidents and daily messes. Your home stays fresh, clean, and free from worry.
It works on carpets, floors, and drains. Odors from dogs, cats, and humans fade quickly.
It’s safe for most surfaces and your family. This cleaner handles stains, spills, and more with ease.
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Perfect For:
This cleaner is perfect for people with pets like dogs and cats, tackling stains, odors, and messes from urine or vomit. It also fits families who need a safe way to clean carpets, floors, and bathrooms.
Ready to Purchase?
8. Enzyme Laundry Booster Odor Remover – 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood – 64 Loads
Enzyme Laundry Booster is an unscented powder that fights tough odors and stains. It uses bio-active enzymes to clean clothes deep, not just hide smells. This natural formula works with your regular detergent for 64 loads.
Our enzyme powder removes stains like sweat, oil, blood, and grease from clothes. It’s perfect for gym clothes and everyday dirt. Rub it on spots before washing for best results.
This laundry booster works in all washers, front or top load. It’s gentle on fabrics and safe for colors. Add it to your routine for fresher, cleaner clothes every time.
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Perfect For:
The Enzyme Laundry Booster Odor Remover is perfect for people who need to fight tough stains and strong smells on clothes, like sweat, oil, blood, and grease, without harsh chemicals. It’s great for families, athletes, and anyone who wants gentle, natural cleaning that works with any detergent and washer.
Ready to Purchase?
9. Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps | 1 Gallon
Tackle tough clogs and eliminate nasty odors with Green Gobbler Enzyme Drain Cleaner. This powerful formula is designed to break down grease, fats, and food waste in your plumbing.
With anti-glug technology, it reduces mess and makes application easy. Enjoy up to eight treatments from just one gallon. This cleaner is also safe for pipes, making it a smart choice for septic tanks and grease traps.
Keep your plumbing in tip-top shape. Green Gobbler boosts the efficiency of your grease traps. Plus, if you’re not satisfied, there’s a 30-day money-back guarantee.
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Perfect For:
This Green Gobbler product is perfect for anyone with clogged drains or smelly pipes. It’s also great for those who want to keep their septic tanks and grease traps working well.
Ready to Purchase?
10. Nature’s Miracle Urine Destroyer Plus Dog, 32 Ounces, Enzymatic Formula, Ready-to-Use
Nature’s Miracle Urinary Destroyer Plus Dog tackles dog urine messes right away. Just soak the spot and let it sit for 15 minutes. Then blot up the stain with a cloth.
This enzymatic formula keeps working on bio-based stains. It is safe for your pets and home.
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Perfect For:
This product is perfect for dog owners dealing with pesky urine messes in their homes. It helps clean up stains quickly and keeps things fresh for you and your pet.
Ready to Purchase?
Buying Guide
Enzyme cleaners break down tough stains and smells at the source. They use natural enzymes to eat away at dirt. Pick one that fits your needs for a clean home.
Users love how these cleaners work fast. One mom said it wiped out her dog’s urine spot on the carpet in minutes. Another shared that it freshened her trash can without any bad odors left behind.
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Stain Type: Look for cleaners that target pet urine, food spills, or grease. Some handle bio-based messes best. Check the label for what it fights.
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Surfaces It Cleans: Choose one safe for carpets, floors, or fabrics. Not all work on every spot. Test a small area first.
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Size and Amount: Go for a gallon for big jobs or a spray for quick fixes. Smaller bottles suit light use. Think about how much you need.
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Scent Options: Pick fragrance-free if smells bother you. Others leave a fresh hint. Match it to your home’s vibe.
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Safety Level: Seek pet-safe and kid-friendly formulas. Avoid harsh chemicals. Read warnings for peace of mind.
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How Long It Works: Some enzymes keep cleaning for days or weeks. This stops smells from coming back. Look for long-acting types.
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Price Value: Balance cost with how much it covers. A bigger bottle often saves money. Check for bundle deals.
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Eco-Friendly Features: Opt for natural blends or septic-safe ones. Many are made in the USA. They help the planet too.